Of the three alternative splicing events validated by RT–PCR in D3H2 cells (Fig. 8A, B and Supplemental Fig. 12), two events, involving exon 40 of the MYO18A gene and exon 3 of the NFYA gene, significantly correlated with Snord67 expression in the primary breast and LN tumor specimens from breast cancer patients (MYO18A exon 40: Pearson r = 0.46, p = 0.0009; NFYA exon 3: Pearson r = 0.49, p = 0.0006; Fig. 8C, D). Here, NFYA is linked to breast cancer.