APP and Alzheimer disease: In sharp contrast, the expression of ADan fusion leads to 25.14 ± 3.41% of the cells growing in selection media over nonselective conditions, a twofold increase compared to the growth rate induced in the same conditions by the amyloid-beta peptide (Aβ42), the peptide that forms amyloids in Alzheimer’s disease and is mutated in familial forms of the disease (16) (Fig. 1C and SI Appendix, Fig. S1B).