These factors include blood creatinine, ZAG [5], sclerostin miRNA-29b [33], FGF-21, IGF-1 [12], Gal-3, MMP-9 [32], LDL [26], pH [15], serum sorting protein [27], Kt/V, serum potassium(K) [17], TyG [18], smoking, pruritus score [34], BMI, calcium-phosphorus product, N-MID OC, β type I collagen cross-linked carboxy-terminal peptide (beta-CTX), cholesterol(TC) [21], sTWEAK [22], coronary heart disease [30], and irisin [13]. The gene discussed is LGALS3; the disease is coronary artery disorder.