Significant predictors of composite endpoint identified at univariate analysis included age, previous CV event, DM status, BMI ≥ 30 kg/m2, FPG at admission, arterial hypertension, CHF, COPD, CT-visual score, treatment with insulin, ASA, beta-blockers, statin, dyspnea at admission, EKG abnormalities, P/F ratio, WBC, NRL, RDW, LDH, CRP, D-dimer, PCT, and eGFR (data not shown). This evidence concerns the gene INS and chronic obstructive pulmonary disease.