The acute myeloblastic leukemia with maturation (former AML-M2 FAB) is often positive for CD13, CD15, CD33, CD34, CD117, HLA-DR and comprises approximately 25-30% of all cases with ≥ 20% blasts in the bone marrow or peripheral blood with ≥ 10% granulocyte differentiation (24). Here, CD33 is linked to acute myeloid leukemia.