When stratified by HTN diagnosis, anti-ETAR autoantibodies were elevated in subjects with an SLE diagnosis irrespective of HTN status, to both non-SLE non-HTN (p < 0.0001 for both) and non-SLE HTN (p < 0.0001 for both) groups (Fig. 2Cand Supplemental Table 9). This evidence concerns the gene EDNRA and hypertensive disorder.