The parallel functions between DIM-3,5 analogs and quercetin can also be extended to their effects on ferroptosis since DIM-3,5-CI2 and DIM-3-CI-5-CF3 induce ROS, lipoperoxidation and MDA formation and also decrease expression of GPX4 and SLC7A11 in TNBC cell lines and similar results have been observed for flavonoids in cancer cells [25–29]. Here, GPX4 is linked to cancer.