This basic design pattern inherited from IDO is generalizable to other fungal infectious diseases, such as when an instance of aspergillus has colonized and grows within a host’s lungs or sinuses, forming an aspergilloma - a fungal infectious disorder - which is the physical basis for MONDO’s aspergillosis - a fungal infectious disease - that may be realized in an aspergillosis infectious disease course. The gene discussed is IDO1; the disease is aspergillosis.