Cardiomyocyte mortality ↓;Pumping function of the heart ↑;Hemodynamics ↑;CK-MB, LDH, BNP ↓;Myocardial tissue damage ↓;The area of myocardial fibrosis ↓;Myocardial pathologic hypertrophy ↓. Here, NPPB is linked to Myocardial fibrosis.