In addition, expression analysis of those key genes in HCC tissues compared to normal tissues demonstrated that EXO1, PARP1, H2AX, BRCA1, RAD51, CCNB1, CDK1, CDC25C, and CCNE2 were overexpressed in HCC tissues, further supporting the role of these genes in HCC progression (Figure 2E). The gene discussed is CCNB1; the disease is hepatocellular carcinoma.