Both GCNIS and seminoma are strongly positive for OCT3/4, SALL4, and CD117, while embryonal carcinoma express OCT3£ and CD30, and yolk-sac tumors are negative for OCT3/4 and positive for SALL4 and glypican (Al-Obaidy and Idrees, 2021). This evidence concerns the gene TNFRSF8 and seminoma.