Through ROC curve analysis, it was found that the individual analysis of Lp-PLA2, LDL-C, HDL-C, Leukocyte, hs-CRP, FPG, and HbA1c levels had limited value in predicting the prognosis of AIS in T2DM, as multiple factors can interfere with the sensitivity and specificity of the assessment. This evidence concerns the gene PLA2G7 and type 2 diabetes mellitus.