F. nucleatum can secrete multiple virulence factors, including Fusobacterium adhesin A (FadA), encoded by the gene fadA, which is found at elevated levels in CRC patients’ fecal macrogenome [6,7], with a high affinity for cadherin on the surface of CRC cells, enhancing the attachment of F. nucleatum to CRC cells and avoiding clearance by the immune system [8]. The gene discussed is CDH17; the disease is colorectal carcinoma.