Notably, we identified 5 novel QTLs for genes previously implicated in AMD (ACAD10, HTRA1, B3GLCT, PLA2G12A, BAIAP2L2) and 4 genes implicated in AMD without replication of a previously characterised eQTL (CFI, COL4A3, RDH5, TNFRSF10A). The gene discussed is RDH5; the disease is age-related macular degeneration.