CD68 and Alzheimer disease: The results revealed that the expression of CD68 significantly increased, and the expression of CD206 and Arg-1 obviously decreased in AβO-induced AD model mice with respect to control mice; PF treatment reversed the expression of CD206 and Arg-1 with a significant effect at the concentration of 1 mg/kg and the expression of CD68 in a concentration-dependent manner in AβO-exposed mice (Figure 4A-D; P < .05).