A comparison of hallmark pathways of MSigDB in the four cancer cell lines and in HFF cells revealed 11 shared gene sets (KRAS signaling up, KRAS signaling down, Coagulation, IL6-JAK-STAT Signaling, TNFa Signaling via NFκB, Unfolded protein response, Myc targets v2, Mtorc1 signaling, Mitotic Spindle, E2F targets, G2M checkpoint). The gene discussed is TNF; the disease is cancer.