A trend for correlation between higher levels of CD8 + T cells in the tumor nests and longer OS (p = 0.131) (Fig. 4C) was also detected, and the percentage of CD8 + T cells in the tumor nests and stroma correlated inversely with change in tumor size (p = 0.003 and p = 0.006, respectively) (Fig. 4D). The gene discussed is CD8A; the disease is neoplasm.