The levels of the myeloid cell-secreted cytokines tumor necrosis factor (TNF), C–C motif chemokine ligand 3 and 4 (CCL3 and CCL4), and monocyte chemoattractant protein- 4 (MCP- 4) increased significantly with treatment, while Galectin- 9, involved in tumor immune evasion, decreased (Fig. 3B). This evidence concerns the gene CCL3 and neoplasm.