When divided based on median survival time, the five patients with > 80 days (range 84–847 days) since previous ICI discontinuation had higher expression of PD-L1 on tumor cells compared to six patients with < 80 days (range 28–76 days) since the last ICI treatment (Fig. 2D), potentially indicating that PD-L1 expression may have been reduced by treatment and then recovered over time. The gene discussed is CD274; the disease is neoplasm.