To the Editor: Garrigue et al. identified a biallelic variant in the human oncostatin M (OSM) gene in a consanguineous family (3 patients) with inherited severe bone marrow failure syndromes (IBMFS) in the patients aged from 10–20 years, with 4.4 years median age of onset, and in vitro and in vivo experiments established OSM roles in hematopoiesis (1). This evidence concerns the gene OSM and inherited bone marrow failure syndrome.