CRP and Splenomegaly: we built the CRP-A nomogram model based on serum CRP level (>26.8 mg/L), age > 60 years, hepatomegaly and/or splenomegaly, HGB ≤80 g/L, and PC type, which demonstrated robust discriminative performance in stratifying the 1-year, 3-year, and 5-year survival of iMCD patients.