Additionally, baseline age > 60 years (OR=2.599, 95% CI=1.525-4.430, p<0.001), primary disease being diabetic nephropathy (compared to glomerulonephritis, OR=2.326, 95% CI=1.265-4.279, p=0.007), hemoglobin < 110 g/L (OR=2.032, 95% CI=1.291-3.199, p=0.002), and serum albumin < 30 g/L (OR=3.341, 95% CI=2.082-5.361, p<0.001) are also independent risk factors for all-cause mortality in CKD patients by multivariate Cox regression analysis. The gene discussed is ALB; the disease is diabetic kidney disease.