Results of the BRIGHT study31 (a head-to-head randomized controlled trial comparing Gla-300 and IDeg-100 insulin-naive patients with uncontrolled type 2 diabetes) revealed similar improvement in glycemic control and similar rates and incidence of hypoglycemia for Gla-300 and IDeg, with the exception of lower rates with Gla-300 in the titration period. Here, INS is linked to type 2 diabetes mellitus.