A higher level of IL-4 and IFN-γ was observed on Day 11 in the AD group compared with the other three groups; though on Day 15, the trend of these two cytokines' AD group changed contrarily, with downregulating IL-4 (p < 0.01) and upregulation IFN-γ (p < 0.01). This evidence concerns the gene IFNG and Alzheimer disease.