Figures 1B, C depict the marker genes for each of these cell subpopulations. Among them, high expression of CD3D and NKG7 was observed in NK/T cells; EPCAM in epithelial cells; VWF in endothelial cells; CD163 in macrophages; COL1A1 and ACTA2 in fibroblasts; CD79A in B cells; and TPSAB1 and CPA3 genes in mast cells. Analysis of the distribution of various cell types between the benign and tumor groups revealed that, compared to the benign group, NK/T cells exhibited the highest proportional increase in the tumor group (Figure 1D). The gene discussed is COL1A1; the disease is neoplasm.