Other potential biomarkers include serum alpha-L-fucosidase (AFU), gamma-glutamyl transpeptidase isoenzyme II (γ-GT2), des-gamma-carboxy prothrombin (DCP), and Golgi protein 73 (GP73), all of which have shown promise in diagnosing and differentiating HCC (185). The gene discussed is ACE; the disease is hepatocellular carcinoma.