After the completion of the first cycle of TIP chemotherapy, the CT scan indicated that the right para-iliac and periaortic lymph nodes were diminished and contracted (Figure 2C), the cancer thrombus in the inferior vena cava was remarkably reduced (Figure 2F), the metastatic tumors in both lungs were decreased (Figure 3C), AFP was 3.58 ug/L, HCG was 0.6 IU/L and the comprehensive clinical efficacy evaluation was a partial response (PR). This evidence concerns the gene AFP and cancer.