Menopausal status (premenopausal: SHR 1.52, 95% CI: 1.12–2.06, postmenopausal as a reference), HER-2 status (positive: SHR 2.29, 95% CI: 1.71–3.03, negative as a reference), lung metastasis (metastasis: SHR 2.01, 95% CI: 1.53–2.65, no metastasis as a reference) and bone metastasis (metastasis: SHR 1.89, 95% CI: 1.43–2.50, no metastasis as a reference) remained as independent prognostic factors for liver metastasis and were used to construct nomogram. The gene discussed is ERBB2; the disease is bone metastasis.