This result was not similar for the occurrence of falls, which is contrary to the result found in a meta-analysis that revealed the risk of falls was 162% higher for older adults with T2DM who use insulin.25 The use of insulin that may cause hypoglycemia26 or intensive control A1C ≤6 has been linked to a higher risk of falls.27 The role of polypharmacy and medications that may lead to falls in older patients has been studied extensively, indicating the same precaution is necessary for older patients with diabetes. This evidence concerns the gene INS and diabetes mellitus.