Indeed, our interrogation of publicly available patient expression data from LGG patients confirmed a positive correlation between L1CAM and the predominant isoform GSK3B in IDHmut gliomas (Fig. 1f, source: CGGA) and showed that GSK3B is significantly upregulated in IDHmut glioma patients (Fig. 1g, source: CGGA). Here, GSK3B is linked to central nervous system cancer.