Gliomas are the most common primary malignant brain tumors [1] and are classified based on the presence or absence of isocitrate dehydrogenase (IDH) mutations into IDH wildtype (IDHwt) and IDH mutant (IDHmut) tumors, which are biologically distinct entities with significant differences in growth dynamics and prognosis. This evidence concerns the gene IDH2 and brain neoplasm.