GRB10 and fetal growth restriction: Though it should be emphasized that the results from UPD7M/UPD7qM and GRB10DEL patients were achieved from different tissues and are based on a small number of samples, our data allow to delineate their contribution to the SRS phenotype:IUGR as the prenatal phenotype of upd(7)mat is caused by defective paternal alleles of the 7q32 region, as well as by overexpression of the maternal GRB10 allele [23] whereas defective GRB10 paternal alleles do not cause this feature.