Specifically, BCG vaccination expands multiple myeloid subsets, including the lineage (Lin)−Sca- 1+c-kit+ (LSK) and granulocytic-macrophage progenitors (GMPs), and increases CD11b+Gr1+ cell number, as well as their oxidative metabolism and capacity to stimulate T-cell proliferation in response to sepsis. The gene discussed is KIT; the disease is Sepsis.