For example, through in-depth proteomic analysis of liver cancer parenteral fluid, Jian Zhang’s team discovered a novel liver cancer candidate serum marker that is more sensitive and accurate than alpha-fetoprotein and represents the successful application of interstitial fluid in the discovery of cancer serum biomarkers16.In this study, a mouse model of pulmonary fibrosis was established by intratracheal injection of bleomycin. Here, AFP is linked to pulmonary fibrosis.