This metabolic shift subsequently modulates the expression of CXCL14 (C-X-C Motif Chemokine Ligand 14), a protein implicated in the regulation of macrophage homeostasis, contributing to the polarization of M0-type tumor-associated macrophages (TAMs) towards the M2 phenotype, which is associated with enhanced motility and proliferative capacity of NB cells [157]. Here, CXCL14 is linked to neoplasm.