Finally, we further verified several newly identified m6A-modified sites in ALS risk genes, including Dctn1, Epha4, C9orf72, Glt8d1, Cacna1h, Chrna3, Bscl2, Fig4, Hnrnpa2b1, Ubqln2, Hnrnpa1, Tuba4a, Sod1, Chmp2b, and PIKfyve (Supplementary Fig. 6b). This evidence concerns the gene CACNA1H and amyotrophic lateral sclerosis.