VEGFD and cyst: Argulaet al. [87] reported no correlation between qCT-derived lung cyst volume or number with change in FVC, forced expiratory volume in 1 s or serum vascular endothelial growth factor-D, but did suggest that the observed variation in respiratory cycle cyst volume demonstrated the beneficial effect of sirolimus on airflow obstruction, highlighting a role for qCT in mechanistic studies.