Secondly, we have found a protective recessive association between a missense variant in solute carrier (SLC) family 5 member 9 (SLC5A9) (chr1:48228922G>A, rs61746559) hypertension (OR = 0.2, p = 3 × 10−8, dominance deviation p = 7 × 10−6). The gene discussed is SLC5A9; the disease is hypertensive disorder.