PNPLA3 and metabolic dysfunction-associated steatotic liver disease: Firstly, we found a recessive association between rs66812091 (chr22:43939790TGG>T), an intronic variant in PNPLA3 (patatin-like phospholipase domain-containing protein 3), and NAFLD, with an odds ratio (OR) of 1.3 at a p value of 2 × 10−12.