showed that NUPR1 knockdown in glioblastoma cells reduced the levels of phosphorylated ERK1/2 and p38 MAPK.[38] In contrast, our study revealed that inhibition of NUPR1 in THP1 and BMDM cells did not significantly alter phosphorylated p38 MAPK levels; however, phosphorylated ERK and JNK levels increased significantly, underscoring the differential roles of NUPR1 across various cell types. The gene discussed is NUPR1; the disease is glioblastoma.