Conversely, patients with a history of AKI (OR 0.295, 95% CI 0.131–0.666, p = 0.0033) and higher hs-CRP levels (OR 0.605, 95% CI 0.483–0.757, p < 0.0001) exhibited an increased risk of renal function deterioration. This evidence concerns the gene CRP and acute kidney injury.