However, in a population of 401 drug-resistant patients in Australia, the CC genotype in the ABCB1 C3435T polymorphism was not associated with drug-resistant epilepsy [47], a finding also observed in Ireland [48]; therefore, currently, there is controversy surrounding the role that ABCB1 plays in MDRE, if any. The gene discussed is ABCB1; the disease is epilepsy.