IL17RB and asthma: IL-17RB is a specific component of the receptor for IL-17E, also known as IL-25, a major Th2 response mediator.86 iNKT cells have been shown to play a pathologic role in asthma and airway diseases in mouse models,87–89 and the impact of the lack of IL17RB expression in human iNKT cells on such diseases remains unknown.