We also detected high expression of ATOH1 target genes in the 2 ATOH1 SCLC PDXs (Figure 4G; NES = 2.44, p = 5 × 10−10) and an ATOH1-expressing tumor from the MSK SCLC tumor atlas dataset46 (Figure 4H). Here, ATOH1 is linked to small cell lung carcinoma.