These findings were concordant with in vitro chemosensitivity in established SCLC cell lines, whereby the single available ATOH1-expressing HCC33 cell line was up to 10-fold more resistant to cisplatin and etoposide compared to ASCL1-and NEUROD1-expressing cell lines (Figures S1I and S1J). Here, ATOH1 is linked to small cell lung carcinoma.