DAZ1 and Azoospermia: The AZF (azoospermia factor) region on the Y chromosome comprises critical genes whose microdeletions have a direct impact on spermatogenesis, such as RNA-binding motif protein Y-linked family 1, Ptpn13 Like Y-linked, deleted in azoospermia and DEAD-box Y-linked (Rbmy1, Pry, Daz, and Dby), are directly involved in essential germline-specific processes and hold potential for improving future therapeutic strategies [31].