TGFB1 and colorectal carcinoma: It has been reported that bioinformatic analyses of the CRC-transcriptomes indicated that the lncRNA/PVT1 locus might exert a far-reaching impact on the expression and functions of other key genes within two vital CRC-related signaling pathways, specifically the TGFβ/SMAD and Wnt/β-Catenin pathways.