We also observed a greater propensity for PS exposure in type 1 diabetes platelets compared with healthy control participants following stimulation, with CRP-XL alone (at 1 μg/ml CRP-XL 4356 ± 4719 vs 1165 ± 308, p=0.004 and at 10 μg/ml CRP-XL 10,561 ± 6181 vs 5259 ± 1125, p<0.001) or in combination with SFLLLRN (27,124 ± 10,105 vs 19,801 ± 1455, p=0.001), which are known to induce PS exposure. This evidence concerns the gene CRP and type 1 diabetes mellitus.