INS and type 1 diabetes mellitus: The type 1 diabetes cohort was stratified according to eGDR, dividing into three groups: eGDR<6 mg kg−1 min−1, eGDR 6–8 mg kg−1 min−1 and eGDR>8 mg kg−1 min−1, to represent advanced, mild and normal insulin sensitivity, as per Nyström et al [18].