SPON1 and cancer: Core genes with a higher DC (> 8), EC (> 0.06), LAC (> 2.0), BC(> 200), and NC(> 0.3) in the enriched modules were also expressed differentially in TCGA‐CHOL data (36 tumor samples and 9 adjacent cancer samples), including FGF2, IGF1, CAV1, SPON1, and ADAMTS4 (Figure 5C).