Among the detected notable DEGs, we found that the detected CPB1 is closely related to DCIS.[37] DCIS is considered a precursor state preceding the development of IDC.[38, 39] However, accurately distinguishing atypical ductal hyperplasia (ADH) from low‐grade DCIS remains challenging, leading to numerous women under‐going surgical procedures that may not be necessary. Here, CPB1 is linked to ductal breast carcinoma in situ.