CDH1 and neoplasm: In various solid tumors, including non-small cell lung cancer, the overall quantity of TAMs and the high expression of specific markers (such as CD68 and CD163) are closely related to enhanced EMT characteristics in cancer cells (such as downregulation of E-cadherin and upregulation of vimentin), indicating that EMT features are more pronounced in tumor areas rich in TAMs (33, 64–66).