FOXM1 and hepatocellular carcinoma: Furthermore, research showed that miR-3677-3p binds to FBXO31 and inhibit its expression in hepatitis B-associated hepatocellular carcinoma, this inhibition causes FOXM1 to be less ubiquitinated and degraded, which in turn encourages the growth of HCC and sorafenib resistance (He et al., 2023a).