PPARA and Insulin resistance: The DEGs that were enriched in KEGG pathways involved metabolism (metabolic pathways, metabolism of xenobiotics by cytochrome P450, glutathione metabolism, drug metabolism-other enzymes, drug metabolism-cytochrome P450, biosynthesis of unsaturated fatty acids, primary bile acid biosynthesis, other glycan degradation, and retinol metabolism), organismal systems (bile secretion, circadian rhythm, and PPAR signaling pathway), and human diseases (hepatocellular carcinoma, insulin resistance, and pathways in cancer).