TCF7L2 and angina pectoris: Conversely, the TCF7L2 AA genotype was negatively correlated with ACS (r = -0.084, p = 0.022), and the TCF7L2 AC genotype was negatively correlated with both stable angina (r = -0.114, p = 0.001) and ACS (r = -0.131, p = 0.0003) (Figure 1).