In acute COVID-19, positive correlations between APTT, TT, and several inflammatory markers (e.g., IL-6, INF-α2, MCP-1, IL-10, IL-18) were found in COVID-19+ pregnant women, at the same time, negative correlations were revealed between thrombin generation (ETP and peak thrombin) and the same set of inflammatory markers. This evidence concerns the gene IL18 and COVID-19.